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Path Of Exile 3.20: 5 Tips To Improve Your Sanctum Run

Jan 12, 2023

Good day, Exiles! In this article, I'd like to share five tips and tricks for completing your Sanctum runs successfully.

The Basics

Let's start with the basics of each Sanctum first. Each full Sanctum consists of 32 rooms a player must go through and is divided into four sections with their respective miniboss encounters at the end of each.

A run is finished upon reaching and defeating the fourth floor boss, Lysia or the optional Beyond Boss encounter that falls after her. While advancing through your Sanctum, you will encounter rooms that will have arrive with Aureus Coins and could later be exchanged to for the Boons that will provide various paths.

You can also encounter a fountain room, which will heal your Resolve. Each fountain room will cost you 150 Aureus Coins and grant you the Major or Minor Boon in addition to healing you. And a Cursed Fountain, which will heal more Resolve but will also inflict the debuff on you. And a Radiant Fountain that will heal your Resolve, grant you a Minor Boon and will remove a random debuff known as Affliction.

An Affliction is a debuff that connectively impact your Sanctum progression or outright precure run and force you to restart.

poe 3.20 Sanctum run

Tip 1

Therefore, the first tip is that you should never pick an option that grants you a random Affliction. For example, an Accursed Prism. In a successful Sanctum run, you should have more Boons than Afflictions and most of your Afflictions should be non-determinable to your build.

Your run will begin by choosing the Relics that will aid you in completing your Sanctum in this stage. Picking your strategy via the right Relics is vital to your run. There are numerous viable strategies, such as stacking Inspiration when you gain an Affliction or stacking additional boots that the merchant can offer. However, a good and successful strategy should be a mix of everything. For example, I like to use Auspicious Coffee Relics Of Youth since they enable me to stack Resolve. In addition, I also use the Adaptable Papyrus Relic Of Empowerment, which gives me an extra Inspiration.

When I gain an Affliction to trade hits without taking any result damage directly, the remaining slots should be filled with additional merchant offers or additional revealed rooms. This strategy allows me to buff through the fountain notes to stand fully Resolve and efficiently utilize the Curse Facts that lower my Maximum Resolve but provide Boons in return.

Another viable strategy is to stack the chance to gain double Aureus Coins and have extra Aureus Coins at the beginning of your Sanctum run. In addition to extra puns offered by merchant, the idea behind the strategy is to always go for a merchant room and buy up her entire stock. So, she has to provide you with Boons in each encounter and a number of them is limited by stacking as many Boons as possible.You can increase the chances of getting better game-changing major pawns from the merchant.

Related: Path Of Exile 3.20: 8 Reasons Why You Are Failing The Forbidden Sanctum

Tip 2

After picking and confirming your Relics the Sanctum run will begin. The second tip is an essential one and many players choose to either disregard it or ignore it. The first 16 rooms or two floors should be used exclusively to acquire buffs. Skip any lucrative rewards, such as Chaos Orbs or Stacked Decks and path exclusively via treasure fountains merchant or accurate Spectrums. Avoid stacking Afflictions at the stage and if you have to go for non-game breaking. Once as you advance to higher floors, the rewards offered will ramp up. The value with the most lucrative currencies will being offered to you on the third and fourth floors.

Tip 3

The third tip is if you are offered a gamble currency as your reward, you should never pick any of the two deferred options. There are two Boons that can duplicate an additional or up to three additional rewards. Therefore, you should only go for Chaos Orbs, Stacked Decks, solid orbs, Divine Orbs and very rarely sacred orbs.

poe 3.20 Rediant Fountain

Tip 4

When you reach the third and fourth floors, if you do not see any Divine orders being offered to you, you should always pass through the Accurate Spectrums as you might still get it as a random hidden reward.

Tip 5

Finally, the last tip that I want to share with you is you should know the strengths and weaknesses of yourself and your bill. For example, incorporate extra sustaining the uralic strategy, if you are playing a build that has to trade hits. Likewise, if you are a player that can attract well under pressure, avoid an Affliction that gives all monsters an onslaught buff, which is third person attack cast and movement speed. If you tend to forget about volatile projectiles, do not pick an Affliction that will release them upon killed monsters.

The true beauty of this league mechanic is that it becomes what you make of it. There are many viable strategies that you can choose from. And the mechanicals force you to adapt as you progress farther into your Sanctum run. All of this combines to create a very unique experience that vastly differs from the base gameplay of Path of Exile.

By the way, if you want to run the Sanctum more easy, you can also choose to use Divines Orbs or Chaos Orbs to make good builds.

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Next: Review Of League Mechanics In Path Of Exile The Forbidden Sanctum
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