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How To One-Hit An Enemy With Ambusher Strike Assassin In POE 3.23? - Viper Strike Of The Mamba & Ambush

Jan 09, 2024

Hello, exiles! Today, I will teach you how to become an Ambusher Strike Assassin. We’ll sneak up behind the enemy and knock them out with one shot!

Skill

We’ll start with the key skill of this build, Viper Strike of the Mamba, which is a new skill for this Affliction League. It deals with high poison damage, dealing 200% more damage, but you can only have one stack of poison.

How To One-Hit An Enemy With Ambusher Strike Assassin In POE 3.23? - Viper Strike Of The Mamba & Ambush

Now we have a skill that can be combined with this, and that’s Ambush skill. This skill will teleport to the enemy, giving the enemy a buff that increases critical hit rate and critical hit multiplier. This buff will give you a lot of critical hit chance base, helping you reach 100% critical hit chance.

POE 3.23: Viper Strike of the Mamba

Critical Hit Multiplier

Now that we have 100% critical hit chance, the next thing we need is a critical hit multiplier. If you have a higher POE Currency budget, you can use an Amulet called Marylene’s Fallacy. This Amulet increases critical strike multiplier to 240%.

But it has a drawback, this Amulet will reduce your critical hit rate by 40%. Don’t worry, because our Ambush skill has a lot of base critical hit chance, and adding a little of critical hit chance through the passive skill can still reach 100% critical hit chance.

One thing you need to know is that the critical hit multiplier does not increase the damage of poison. But don’t worry, because we have Perfect Agony Keystone Passive, which will give you damage over time multiplier of 50% critical multiplier.

POE 3.23: Marylene's Fallacy

Now, we have critical hit damage multiplied over time too much, but the one thing we don’t have is increased damage. To solve this problem, we use a passive approach called Low Tolerance. This passive will give you 300% more poison damage if the enemy doesn’t already have poison.

Since we’re only playing 1 stack of poison, this passive has no downside for us. And this passive is unlimited, which means you can use it as much as you want.

Weapon

Viper Strike attack skill is slightly more special than the other skills. This skill has a special tag that says, “If a weapon is used with two hands, it will deal damage to both weapons simultaneously.”

With this label, I recommend Rebuke of the Vaal. Since the sword has base damage, about 600 units are mixed with elements. This means that if we use it with both hands, it is equivalent to using a weapon with base damage of 1200 units. Its damage is close to that of a Mirror-Tier weapon, but only requires the budget of 1 Chaos Orb.

POE: Rebuke of the Vaal & Poisonberry Tincture

Tincture

Now that we have a powerful weapon, don’t forget that a sword’s base damage is a mix of elements. As you know, damage caused by Fire, Lightning, and Cold does not count as Poison. That’s why we need to use a new item in Affliction League called Poisonberry Tincture.

Tincture is a new flask added in this league. You can only use it if you have Coated Blade passive skill in Wildwood Ascendancy class.

Tincture has the effect of poisoning all damage types. This will help you convert all damage done with Rebuke of the Vaal into poison damage.

How To Increase Poison Damage?

Now we have a powerful single layer of poison, but we can double this damage using Alchemist’s Mark skill. When you apply poison to an enemy, this mark creates Caustic Ground, dealing 80% damage equal to the strongest poison.

And we only have one poison stack on the enemy, which means this skill will double your damage.

POE: Alchemist's Mark

As you can see, this combo only deals with high damage to a single target. This skill does not clear AOE of the map. To make the map smoother, we need the passive skill from Pathfinder class, which is Master Toxicist.

When you kill a poisoned enemy, their poison will separate into nearby enemies. This means that if you kill one of them, all the monsters in the group will die like this!

Defensive

For the defensive part, you can adapt it to your play style. All the other items I didn’t mention are not fixed, and you can play with whatever armor or evasion you like. So feel free to customize them to your needs.

This guide may not cover the details of every item. I’ll just tell you the core concepts of my build. I know everyone has their own play style, so feel free to customize it however you want!

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